STF-118804

STF-118804

Biochem/physiol Actions

STF-118804 is a highly specific and potent NAMPT (nicotinamide phosphoribosyl transferase) inhibitor that reduces the viability of most B-ALL cell lines. STF 118804 induces leukemia cell apoptosis including leukemia initiating (stem) cells. STF 118804 improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia.

STF-118804 displays pancreatic ductal adenocarcinoma (PDAC) growth reducing potential in combination with chemotherapeutic drugs.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3574784 STF-118804 white to beige 100 DLFCEZOMHBPDGI-UHFFFAOYSA-N 1S/C25H23N3O4S/c1-17-5-11-22(12-6-17)33(30,31)16-23-18(2)32-25(28-23)21-9-7-20(8-10-21)24(29)27-15-19-4-3-13-26-14-19/h3-14H,15-16H2,1-2H3,(H,27,29)
£479.17 (exc VAT) per 25MG
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3574785 STF-118804 white to beige 100 DLFCEZOMHBPDGI-UHFFFAOYSA-N 1S/C25H23N3O4S/c1-17-5-11-22(12-6-17)33(30,31)16-23-18(2)32-25(28-23)21-9-7-20(8-10-21)24(29)27-15-19-4-3-13-26-14-19/h3-14H,15-16H2,1-2H3,(H,27,29)
£146.25 (exc VAT) per 5MG
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