SR-4995

Biochem/physiol Actions

SR-4995 is a potent and selective ligand of α-β-hydrolase domain containing 5 (ABHD5) that activates adipose triglyceride lipase (ATGL) by dissociating ABHD5 from its inhibitory regulator, perilipin-1 (PLIN1) and PLIN5. SR-4995 directly binds to ABHD5 and prevents ABHD5 to PLIN1. SR-4995 induces lipolysis in adipocytes and muscle, avoiding PKA-dependent signaling.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575960 SR-4995 white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£501.43 (exc VAT) per 25MG
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3575961 SR-4995 white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£124.24 (exc VAT) per 5MG
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