SR-18292 MALEATE

SR-18292 MALEATE

Application

SR-18292 Maleate has been used as a peroxisome proliferator-activated receptor ? coactivator 1 ? (PGC1?) inhibitor to study the protective effects of pioglitazone on demyelinated axons.

Biochem/physiol Actions

SR-18292 is a potent and specific inhibitor of hepatic gluconeogenesis via increased acetylation of PGC-1α and suppression of gluconeogenic gene expression. SR-18292 reduces blood glucose and increases hepatic insulin sensitivity in mouse models of T2D.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575872 SR-18292 MALEATE white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
£515.36 (exc VAT) per 25MG
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3575873 SR-18292 MALEATE white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
£196.39 (exc VAT) per 5MG
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