Spermine tetrahydrochloride, BioReagent, for molecular biology

Descriptions

Application

Used to precipitate DNA from low salt aqueous buffers.

Biochem/physiol Actions

Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

Mixed NMDA agonist/antagonist at the polyamine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

General description

Spermine is a polyamine involved in cellular metabolism and DNA stabilization. In molecular biology it can be used in buffers for purification of DNA.

Specifications

No detailed specifications are available for this product.

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Code	Description	Quality Level	mp	InChI key	InChI	Manufacturer	Product Line	Form	Price	Quantity
3582131	Spermine tetrahydrochloride, BioReagent, for molecular biology	300	310-311 °C (dec.) (lit.)	XLDKUDAXZWHPFH-UHFFFAOYSA-N	1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H	SIGMA-ALDRICH	BioReagent	solid	£549.64 (exc VAT) per 10G	- +
3582132	Spermine tetrahydrochloride, BioReagent, for molecular biology	300	310-311 °C (dec.) (lit.)	XLDKUDAXZWHPFH-UHFFFAOYSA-N	1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H	SIGMA-ALDRICH	BioReagent	solid	£76.68 (exc VAT) per 1G	- +
3582133	Spermine tetrahydrochloride, BioReagent, for molecular biology	300	310-311 °C (dec.) (lit.)	XLDKUDAXZWHPFH-UHFFFAOYSA-N	1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H	SIGMA-ALDRICH	BioReagent	solid	£266.00 (exc VAT) per 5G	- +