Somatostatin, >=97% (HPLC), powder

Somatostatin, >=97% (HPLC), powder

Amino Acid Sequence

Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys

Application

Somatostatin has been used:as a standard antigen to detect antibodies in an indirect enzyme-linked immunosorbent assay (ELISA) methodto study the effect of somatostatin on oxytocin release during pregnancy in ratsto test the specificity of the avidin-biotinylated horseradish peroxidase immunocytochemical procedure to visualize somatostatin-immunoreactive (SS-IR) neurons

Biochem/physiol Actions

Somatostatin (SST) performs several functions like anti-proliferation, pro-apoptosis and anti-migration. Somatostatin performs physiological activities with the help of various G protein-coupled receptor subtypes (SST receptor (SSTR)-1, SSTR2A, SSTR2B, and SSTR3-5).

Somatostatin regulates the secretion of hormones and bioactive peptides. It acts as an inhibitor in the digestive tract by inhibiting gastrin release. In the pancreatic islets, it inhibits glucagon and insulin release. Somatostatin and its synthetic analogs have been used in the treatment of neuroendocrine tumors.

General description

Somatostatin (SST) is a peptide.

Somatostatin is expressed in endocrine cells and nerve fibers of the gastrointestinal tract. It is also expressed in other tissues.

Other Notes

Lyophilized from 0.1% TFA in H2O

Packaging

1, 5, 10 mg in glass bottle

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Code Description Quality Level InChI key InChI Manufacturer Storage Temp. Form Assay Price Quantity
3592236 Somatostatin, >=97% (HPLC), powder 200 NHXLMOGPVYXJNR-FQSIDJEASA-N 1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90 SIGMA-ALDRICH
£92.63 (exc VAT) per EACH
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3592237 Somatostatin, >=97% (HPLC), powder 200 NHXLMOGPVYXJNR-FQSIDJEASA-N 1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90 SIGMA-ALDRICH
£956.89 (exc VAT) per 10MG
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3592238 Somatostatin, >=97% (HPLC), powder 200 NHXLMOGPVYXJNR-FQSIDJEASA-N 1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90 SIGMA-ALDRICH
£158.79 (exc VAT) per 1MG
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3592239 Somatostatin, >=97% (HPLC), powder 200 NHXLMOGPVYXJNR-FQSIDJEASA-N 1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90 SIGMA-ALDRICH
£614.25 (exc VAT) per 5MG
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