SNS-032

Biochem/physiol Actions

SNS-032 (BMS-387032) is a selective and potent inhibitor of cyclin-dependent kinases (Cdks) 2, 7, and 9 that regulate the cell cycle and transcription. It has IC50 values of 38 nM for Cdk2, 62 nM for Cdk7, and 4 nM for Cdk9. SNS-032 was in clinical trials for a variety of cancers including chronic lymphocytic leukemia (CLL) and multiple myeloma (MM).

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Code Description Colour InChI key InChI Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575978 SNS-032 white to beige OUSFTKFNBAZUKL-UHFFFAOYSA-N 1S/C17H24N4O2S2/c1-17(2,3)12-8-19-13(23-12)10-24-14-9-20-16(25-14)21-15(22)11-4-6-18-7-5-11/h8-9,11,18H,4-7,10H2,1-3H3,(H,20,21,22) SIGMA-ALDRICH
£349.61 (exc VAT) per 25MG
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3575979 SNS-032 white to beige OUSFTKFNBAZUKL-UHFFFAOYSA-N 1S/C17H24N4O2S2/c1-17(2,3)12-8-19-13(23-12)10-24-14-9-20-16(25-14)21-15(22)11-4-6-18-7-5-11/h8-9,11,18H,4-7,10H2,1-3H3,(H,20,21,22) SIGMA-ALDRICH
£107.95 (exc VAT) per 5MG
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