SJ000291942

SJ000291942

Biochem/physiol Actions

SJ000291942 is an activator of Bone Morphogenetic Protein (BMP) signaling with an EC50 value ﹤ 1 µM. Bone Morphogenetic Proteins (BMPs) are a group of growth factors and cytokines were originally discovered by their ability to induce the formation of bone and cartilage, but are now considered to constitute a group of pivotal morphogenetic signals, orchestrating tissue architecture throughout the body. SJ000291942 was shown to ventralize zebrafish embryos, activate SMAD1/5/8 phosphorylation, and induce the differentiation of C2C12 myoblasts to osteoblasts in manner consistent with BMP4 activation.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575800 SJ000291942 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£447.11 (exc VAT) per 25MG
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3575801 SJ000291942 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£117.98 (exc VAT) per 5MG
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