SAUCHINONE

SAUCHINONE

Biochem/physiol Actions

Sauchinone is an anti-inflammatory and antioxidant lignan isolated from Saururus chinensis a medical plant used for the treatment of fever, jaundice, oedema and inflammatory disease in oriental folk medicine. Sauchinone inhibits LPS-inducible iNOS (NOS II), TNF-α and COX-2 expression in macrophages through suppression of IKBα phosphorylation. It appears that sauchinone protects against myocardial ischemia/reperfusion injury by inhibition of p28 phosphorylation.

Features and Benefits

This compound is featured on the Nitric Oxide Synthases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level Manufacturer Solubility Form Assay Price Quantity
3574115 SAUCHINONE white to beige 100 SIGMA-ALDRICH DMSO: 5 mg/mL, clear (warmed) powder ≥98% (HPLC)
£469.39 (exc VAT) per 25MG
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3574116 SAUCHINONE white to beige 100 SIGMA-ALDRICH DMSO: 5 mg/mL, clear (warmed) powder ≥98% (HPLC)
£162.96 (exc VAT) per 5MG
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