SAJM589

SAJM589

Biochem/physiol Actions

sAJM589 is a Myc inhibitor that disrupts the Myc-Max heterodimer with an IC50 value of 1.8 µM. sAJM589 was shown to suppress cellular proliferation in a variety of MYC-dependent cancer cell line including strong inhibition of Burkitt lymphoma Raji cell line growth. The mechanism of action of sAJM589 is thought to involve increased ubiquitination of Myc by inhibition of Max binding to Myc, leading to proteasome-mediated degradation.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575946 SAJM589 yellow to orange SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear (warmed)
£380.25 (exc VAT) per 25MG
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3575947 SAJM589 yellow to orange SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear (warmed)
£117.98 (exc VAT) per 5MG
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