RWJ 67657

RWJ 67657

Biochem/physiol Actions

RWJ 67657 is an orally active, potent and selective inhibitor of p38α and p38β MAP kinases. RWJ 67657 inhibits the release of TNF-α and IL-1β from LPS induced blood mononuclear cells. It exhibits cardioprotective and anti-inflammatory activities in vivo.

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Code Description Colour InChI key InChI Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575966 RWJ 67657 white to beige QSUSKMBNZQHHPA-UHFFFAOYSA-N 1S/C27H24FN3O/c28-24-13-11-22(12-14-24)26-27(23-15-17-29-18-16-23)31(25(30-26)10-4-5-20-32)19-6-9-21-7-2-1-3-8-21/h1-3,7-8,11-18,32H,5-6,9,19-20H2 SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
£360.05 (exc VAT) per 25MG
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3575967 RWJ 67657 white to beige QSUSKMBNZQHHPA-UHFFFAOYSA-N 1S/C27H24FN3O/c28-24-13-11-22(12-14-24)26-27(23-15-17-29-18-16-23)31(25(30-26)10-4-5-20-32)19-6-9-21-7-2-1-3-8-21/h1-3,7-8,11-18,32H,5-6,9,19-20H2 SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
£115.61 (exc VAT) per 5MG
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