Rp-8-Bromo-beta-phenyl-1,N2-ethenoguanosine 3,5-cyclic monophosphorothioate sodium salt, >=98% (HPLC

Descriptions

Biochem/physiol Actions

Rp-8-Br-PET-cGMPS is metabolically stable, competitive inhibitor of cGMP-dependent protein kinase G. Inhibits both PKG I (K_i?=?30 nM) and PKG II and blocks cGMP-gated retinal type ion channels (IC_50?=?25 micromoles).

Features and Benefits

This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

U.S. Patent 5,625,056, DE Patent 4,217,679.

Packaging

1, 5 mg in glass bottle

Specifications

No detailed specifications are available for this product.

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Code	Description	Colour	Quality Level	mp	InChI key	InChI	Manufacturer	Form	Assay	Price		Quantity
3573287	Rp-8-Bromo-beta-phenyl-1,N2-ethenoguanosine 3,5-cyclic monophosphorothioate sodium salt, >=98% (HPLC	white to beige	100	240-300 °C (lit.)	SVMPQLHYWRTQCX-DBHVCDLJSA-M	1S/C18H15BrN5O6PS.Na/c19-17-21-11-14(24(17)16-12(25)13-10(29-16)7-28-31(27,32)30-13)22-18-20-9(6-23(18)15(11)26)8-4-2-1-3-5-8;/h1-6,10,12-13,16,25H,7H2,(H,20,2	SIGMA-ALDRICH	powder	≥98% (HPLC)	£385.82 (exc VAT) per 1MG		- +
3573288	Rp-8-Bromo-beta-phenyl-1,N2-ethenoguanosine 3,5-cyclic monophosphorothioate sodium salt, >=98% (HPLC	white to beige	100	240-300 °C (lit.)	SVMPQLHYWRTQCX-DBHVCDLJSA-M	1S/C18H15BrN5O6PS.Na/c19-17-21-11-14(24(17)16-12(25)13-10(29-16)7-28-31(27,32)30-13)22-18-20-9(6-23(18)15(11)26)8-4-2-1-3-5-8;/h1-6,10,12-13,16,25H,7H2,(H,20,2	SIGMA-ALDRICH	powder	≥98% (HPLC)	Click Add to Quote for price and delivery		- +