ROSEOFLAVIN

ROSEOFLAVIN

Biochem/physiol Actions

Roseoflavin is an analog of flavin mononucleotide (FMN) and riboflavin with antimicrobial activity. Roseoflavin is converted to the flavin mononucleotide (FMN) analog roseoflavin mononucleotide (RoFMN) by flavokinase and to the flavin adenine dinucleotide (FAD) analog roseoflavin adenine dinucleotide (RoFAD) by FAD synthetase, and acts as a riboflavin antagonist. Roseoflavin is an inhibitor of bacterial riboflavin riboswitches, cis regulatory elements present in non-coding RNA that specifically bind to natural ligands to regulate gene expression. Roseoflavin, converted to RoFMN, blocks the flavin mononucleotide riboswitch-mediated expression of the ribB gene, which is required for riboflavin biosynthesis.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3575119 ROSEOFLAVIN faint red to very dark brown-red 100 IGQLDUYTWDABFK-UHFFFAOYSA-N 1S/C18H23N5O6/c1-8-4-9-11(5-10(8)22(2)3)23(6-12(25)15(27)13(26)7-24)16-14(19-9)17(28)21-18(29)20-16/h4-5,12-13,15,24-27H,6-7H2,1-3H3,(H,21,28,29) SIGMA-ALDRICH DMSO: 5 mg/mL, clear (warmed) powder ≥95% (HPLC)
£527.89 (exc VAT) per 25MG
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3575120 ROSEOFLAVIN faint red to very dark brown-red 100 IGQLDUYTWDABFK-UHFFFAOYSA-N 1S/C18H23N5O6/c1-8-4-9-11(5-10(8)22(2)3)23(6-12(25)15(27)13(26)7-24)16-14(19-9)17(28)21-18(29)20-16/h4-5,12-13,15,24-27H,6-7H2,1-3H3,(H,21,28,29) SIGMA-ALDRICH DMSO: 5 mg/mL, clear (warmed) powder ≥95% (HPLC)
£124.94 (exc VAT) per 5MG
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