RO5256390

RO5256390

Biochem/physiol Actions

RO5256390 is an agonist of Trace amine-associated receptor 1 (TAAR1), a GPCR primarily found in the brain, expressed in areas where the major monoamine amine transmitters (DA and NE) are also present. RO5256390 is a selective TAAR1 agonist shown to be a negative regulator of dopamine transmission. It has antipsychotic activity in models of schizophrenia, reduces cocaine′s reinforcng effects, and blocks binge-eating disorder.

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575512 RO5256390 white to beige 100 SIGMA-ALDRICH 2-8°C
£681.11 (exc VAT) per 25MG
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3575513 RO5256390 white to beige 100 SIGMA-ALDRICH 2-8°C
£136.50 (exc VAT) per 5MG
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