RL5A

RL5A

Biochem/physiol Actions

RL5a is a potent inhibitor of the replication licensing system in human cells. RL5a blocks the binding of the origin recognition complex (ORC) to origin DNA, which is required interaction for licensing. RL5a appears to act as noncompetitive inhibitor of ORC with respect to ATP.

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Code Description Colour InChI key InChI Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575935 RL5A white to very dark brown CRGKLHXVNVZAPA-UHFFFAOYSA-N 1S/C17H19N3O/c1-20(2)10-9-18-15-12-16(17-8-5-11-21-17)19-14-7-4-3-6-13(14)15/h3-8,11-12H,9-10H2,1-2H3,(H,18,19) SIGMA-ALDRICH
£461.04 (exc VAT) per 25MG
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3575936 RL5A white to very dark brown CRGKLHXVNVZAPA-UHFFFAOYSA-N 1S/C17H19N3O/c1-20(2)10-9-18-15-12-16(17-8-5-11-21-17)19-14-7-4-3-6-13(14)15/h3-8,11-12H,9-10H2,1-2H3,(H,18,19) SIGMA-ALDRICH
£142.07 (exc VAT) per 5MG
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