R-IMPP HYDROCHLORIDE

R-IMPP HYDROCHLORIDE

Biochem/physiol Actions

R-IMPP is a potent and selective inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) secretion that stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin. R-IMPP binds selectively to human ribosomes and causes transcript-dependent inhibition of PCSK9 translation.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575742 R-IMPP HYDROCHLORIDE white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
£461.04 (exc VAT) per 25MG
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3575743 R-IMPP HYDROCHLORIDE white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
£121.32 (exc VAT) per 5MG
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