Purmorphamine

Purmorphamine

Application

Purmorphamine has been used to study the consequences of upregulation of Hedgehog signalling pathway in Tupfel long fin strain Zebrafish.

Biochem/physiol Actions

Purmorphamine activates the Hedgehog (Hh) signaling pathway, directly binding to the Smoothened (Smo) receptor. In various studies, purmorphamine has been shown to induce osteoblast differentiation, generate cardiomyocytes from human embryonic stem cells, increase the neuronal differentiation of a human striatal neural stem cell line, and to differentiate human umbilical cord mesenchymal stem cells (hUCMSCs) into motoneurons.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3574185 Purmorphamine white to beige 100 SIGMA-ALDRICH −20°C DMSO: 5 mg/mL, clear (warmed) powder ≥98% (HPLC)
£855.21 (exc VAT) per 25MG
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3574186 Purmorphamine white to beige 100 SIGMA-ALDRICH −20°C DMSO: 5 mg/mL, clear (warmed) powder ≥98% (HPLC)
£218.68 (exc VAT) per 5MG
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