Potter-Elvehjem PTFE pestle and glass tube

Potter-Elvehjem PTFE pestle and glass tube

Tissue grinders produce homogenates by a combination of shearing and compression actions. The tissue sample is progressively ground (sheared) into smaller pieces at the rounded end of the pestle as the spinning pestle is lowered into the tube. As the pestle is forced lower into the tube, the sample is displaced and forced between the straight outside wall of the pestle and the inside wall of the tube, compressing the tissue cells until they rupture. When the tube is pulled away from the pestle, a slight vacuum is created that pulls the sample back past the compression area, resulting in an additional homogenisation stroke. The degree of homogenisation is controlled by the clearance between the pestle's and tube's cylindrical section (radial distance usually 0.002 - 0.003 inches), the rotational speed of the pestle, and the number of compression strokes made. The Potter-Elvehjem tissue grinder has rounded shape on the lower portion of the pestle where the sample is progressively ground smaller.

Manufactured from borosilicate glass 3.3

Sizes 21 to 24 have radial serrations on the lower portion of the pestle to deliver the homogenate into the cylindrical portion of the tube

With PTFE pestle for application with softer tissues

Ungrounded tube

Replacement components are available and completely interchangeable

Clearance between pestles and tubes is 0.004" to 0.006"

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Code Description Price Quantity
3571026 Potter-Elvehjem PTFE pestle and glass tube, working volume 3 mL
£188.05 (exc VAT) per EACH
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3571027 Potter-Elvehjem PTFE pestle and glass tube, working volume 8 mL
£167.60 (exc VAT) per EACH
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