PKUMDL-WQ-2201

PKUMDL-WQ-2201

Biochem/physiol Actions

PKUMDL-WQ-2201 is a potent and selective non-NAD+-competing allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) that selectively inhibits serine synthesis in cancer cells. PKUMDL-WQ-2201 binds to allosteric site II, which is located in the substrate-binding domain. PKUMDL-WQ-2201 inhibits tumor growth of MDA-MB-468 xenografts in mice.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575630 PKUMDL-WQ-2201 white to brown SIGMA-ALDRICH 2-8°C DMSO: 15 mg/mL, clear powder ≥98% (HPLC)
£490.29 (exc VAT) per 25MG
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3575631 PKUMDL-WQ-2201 white to brown SIGMA-ALDRICH 2-8°C DMSO: 15 mg/mL, clear powder ≥98% (HPLC)
£113.52 (exc VAT) per 5MG
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