PKUMDL-WQ-2101

PKUMDL-WQ-2101

Biochem/physiol Actions

PKUMDL-WQ-2101 is a potent and selective non-NAD+-competing allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) that selectively inhibits serine synthesis in cancer cells. PKUMDL-WQ-2101 binds to allosteric site I, which is located close to active site. PKUMDL-WQ-2101 inhibits tumor growth of MDA-MB-468 xenografts in mice.

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575637 PKUMDL-WQ-2101 light yellow to dark orange 100 SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
£490.29 (exc VAT) per 25MG
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3575638 PKUMDL-WQ-2101 light yellow to dark orange 100 SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
£150.43 (exc VAT) per 5MG
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