PKS21004

Biochem/physiol Actions

PKS21004 is highly selective, potent and reversible inhibitor of the Plasmodium falciparum proteasome (Pf20S) β5 subunit. It is not active against mammalian c-20S and i-20S proteasome subunits. PKS21004 is effective against erythrocytic, sexual, and liver-stage parasites. Also it is active against parasites resistant to current antimalarials, and strains from patients in Africa.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576322 PKS21004 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£398.36 (exc VAT) per 25MG
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3576323 PKS21004 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£98.89 (exc VAT) per 5MG
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