PKF118-310, >=98% (HPLC), powder

Biochem/physiol Actions

PKF118-310 is an antagonist of the Tcf4/b-catenin signaling. The compound disrupts the Tcf4/b-catenin complex and inhibits expression of Tcf4 responsive genes. PKF118-310 inhibits expression of survivin and induces apoptosis in HCC, colon tumor and lymphocytic leukemia cell lines.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3573435 PKF118-310, >=98% (HPLC), powder white to light brown 100 SLGRAIAQIAUZAQ-UHFFFAOYSA-N 1S/C7H7N5O2/c1-11-6(13)4-5(10-7(11)14)12(2)9-3-8-4/h3H,1-2H3 SIGMA-ALDRICH H2O: 10 mg/mL, clear powder ≥98% (HPLC)
£747.96 (exc VAT) per 25MG
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3573436 PKF118-310, >=98% (HPLC), powder white to light brown 100 SLGRAIAQIAUZAQ-UHFFFAOYSA-N 1S/C7H7N5O2/c1-11-6(13)4-5(10-7(11)14)12(2)9-3-8-4/h3H,1-2H3 SIGMA-ALDRICH H2O: 10 mg/mL, clear powder ≥98% (HPLC)
£215.89 (exc VAT) per 5MG
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