Pitstop 2

Pitstop 2

Application

Pitstop 2 has been used as an inhibitor of clathrin-mediated endocytosis.

Biochem/physiol Actions

Pitstop 2 is a selective inhibitor of clathrin-mediated endocytosis.

Pitstop 2 also has an ability to breakdown the nuclear pore complex (NPC) permeability barrier and decrease importin ? binding along with alteration of the NPC ultrastructure. Pitstop 2 is also involved in the inhibition of platelet activation, platelet aggregation and secretion.

Pitstop 2 is a selective inhibitor of clathrin-mediated endocytosis that acts via blocking ligand access to the clathrin terminal domain. Pitstop 2 selectively inhibits clathrin-mediated HIV entry and stalls clathrin-coated pit (CCP) dynamics.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3574557 Pitstop 2 white to light brown 100 SIGMA-ALDRICH −20°C
£611.46 (exc VAT) per 25MG
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3574558 Pitstop 2 white to light brown 100 SIGMA-ALDRICH −20°C
£162.96 (exc VAT) per 5MG
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