Phaclofen, solid

Phaclofen, solid

Application

Phaclofen has been used to block GABAB receptor.

Biochem/physiol Actions

Phaclofen plays a vital role in identifying the physiological importance of central and peripheral bicuculline-insensitive receptors with which GABA and (?) baclofen interact. Phaclofen acts as a GABAB receptor antagonist. Phaclofen has an ability to reversibly block the late, bicuculline resistant, K+ dependent inhibitory postsynaptic potential (IPSP) logged in projection cells of the cat and rat dorsal lateral geniculate nucleus and in rat hippocampal CA1 pyramidal neurons.

General description

Phaclofen is a phosphonic acid derivative of baclofen.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. P118.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Packaging

5, 25, 100 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Impurities Form Price Quantity
3591953 Phaclofen, solid white 100 VSGNGLJPOGUDON-UHFFFAOYSA-N 1S/C9H13ClNO3P/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H2,12,13,14)
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3591954 Phaclofen, solid white 100 VSGNGLJPOGUDON-UHFFFAOYSA-N 1S/C9H13ClNO3P/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H2,12,13,14)
£486.11 (exc VAT) per 25MG
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3591955 Phaclofen, solid white 100 VSGNGLJPOGUDON-UHFFFAOYSA-N 1S/C9H13ClNO3P/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H2,12,13,14)
£120.76 (exc VAT) per 5MG
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