PF-562 271

PF-562 271

Application

PF-562,271 has been used as a focal adhesion kinase (FAK) inhibitor to study its effects on the S100A9-induced tumor cell invasion in prostate cancer cell lines. It has also been used to study its effects on syndecan-1 (SDC-1) knockdown-induced upregulation of early growth regulator 1 (EGR1) in colon cancer cells.

Biochem/physiol Actions

PF-562,271 is a potent, ATP-competitive, reversible and selective inhibitor of FAK and Pyk2. PF-562,271 inhibits FAK phosphorylation in vivo.

Legal Information

Pfizer is a registered trademark of Pfizer, Inc.

Sold for research purposes under agreement from Pfizer Inc.

No detailed specifications are available for this product.

There are no downloads for this product.

Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3573854 PF-562 271 white to brown SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£490.29 (exc VAT) per 25MG
-
+
3573855 PF-562 271 white to brown SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£167.14 (exc VAT) per 5MG
-
+