PF-04363467 HYDROCHLORIDE

PF-04363467 HYDROCHLORIDE

Biochem/physiol Actions

PF-4363467 hydrochloride is a Dopamine D3/D2 receptor antagonist. PF-4363467 has 100-fold selectivity for D3 with a Ki value of 3.1 nM for D3R compared to a Ki value of 692 nM for D2R and high selectivity for D3R compared to other biogenic amine receptors. PF-4363467 attenuated opioid drug-seeking behavior in a rat model of addiction without causing the extrapyramidal symptoms often associated with D2R antagonism.

Legal Information

Pfizer is a registered trademark of Pfizer, Inc.

Sold for research purposes under agreement from Pfizer Inc.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level Manufacturer Solubility Form Assay Price Quantity
3573806 PF-04363467 HYDROCHLORIDE white to beige 100 SIGMA-ALDRICH H2O: 3 mg/mL, clear (warmed)
£435.96 (exc VAT) per 25MG
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3573807 PF-04363467 HYDROCHLORIDE white to beige 100 SIGMA-ALDRICH H2O: 3 mg/mL, clear (warmed)
£107.53 (exc VAT) per 5MG
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