P1,P5-Di(adenosine-5) pentaphosphate trilithium salt, >=95%, powder

P1,P5-Di(adenosine-5) pentaphosphate trilithium salt, >=95%, powder

Application

P1,P5-Di(adenosine-5?) pentaphosphate trilithium salt has been used as a adenylate kinase inhibitor and as a component of pre-AMPPNP rigor solution for treating muscle fibres.

Biochem/physiol Actions

A diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5′-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In cardiac muscle, pM to nM concentrations significantly increase the open-probability of ryanodine-receptor (RyR2) gates, with prolonged action due to slow dissociation from the receptor.

Packaging

10, 50 mg in poly bottle

No detailed specifications are available for this product.

There are no downloads for this product.

Code Description Colour Quality Level InChI key InChI Manufacturer Form Assay Price Quantity
3577712 P1,P5-Di(adenosine-5) pentaphosphate trilithium salt, >=95%, powder white to off-white 200 BFBDFBHROZLGEG-JJCYRVQFSA-K 1S/C20H29N10O22P5.3Li/c21-15-9-17(25-3-23-15)29(5-27-9)19-13(33)11(31)7(47-19)1-45-53(35,36)49-55(39,40)51-57(43,44)52-56(41,42)50-54(37,38)46-2-8-12(32)14(34)
£195.00 (exc VAT) per 10MG
-
+
3577713 P1,P5-Di(adenosine-5) pentaphosphate trilithium salt, >=95%, powder white to off-white 200 BFBDFBHROZLGEG-JJCYRVQFSA-K 1S/C20H29N10O22P5.3Li/c21-15-9-17(25-3-23-15)29(5-27-9)19-13(33)11(31)7(47-19)1-45-53(35,36)49-55(39,40)51-57(43,44)52-56(41,42)50-54(37,38)46-2-8-12(32)14(34)
£678.32 (exc VAT) per 50MG
-
+