Oz Biosciences Cas9 Genome Editing mRNA Modified

Descriptions

Cas9 mRNA has been designed to produce high expression level of wild-type endonuclease CRISPR associated (Cas) protein 9. Cas9 mRNA is used to induce site-directed double strand breaks in DNA. These breaks can lead to gene inactivation or introduction of heterologous genes through non-homologous end joining and homologous recombination respectively, providing efficient tool for genome editing. OZ Biosciences mRNAs are produced by in vitro transcription and stabilised at the 5' end by modified nucleotides capping (Cap1). These mature mRNAs contain a poly(A) tail at the 3' end and are also optimised to yield improved stability and performance.

Ready-to-use stabilised Cas9 mRNA

Concentration: 1.0mg/mL in 1mM sodium citrate, pH 6.

#MRNA30 does not bear any additional nucleotide modifications

#MRNA31 is modified with 5-methoxyuridine (5moU) to reduce innate immune responses

#MRNA25 is modified with N1-methyl-pseudouridine (N1-mψ) to reduce innate immune response

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Code	Description	Manufacturer	Price	Quantity
3075023	Oz Biosciences Cas9 Genome Editing mRNA Modified	OZ BIOSCIENCES	£553.93 (exc VAT) per 100UG	- +
3075024	Oz Biosciences Cas9 Genome Editing mRNA Modified	OZ BIOSCIENCES	Click Add to Quote for price and delivery	- +
3075025	Oz Biosciences Cas9 Genome Editing mRNA Modified	OZ BIOSCIENCES	£222.86 (exc VAT) per 20UG	- +