OTX015

OTX015

Biochem/physiol Actions

OTX015 is a potent inhibitor of the BET bromodomain proteins 2, 3, and 4 (BRD2/3/4).

It binds to bromodomain and extra-terminal domain (BET) proteins and inhibits their binding to the chromatin. This in turn prevents gene transcription. OTX015 has been shown to inhibit proliferation of cells in haematological malignancies.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Form Assay Price Quantity
3575144 OTX015 white to light brown 100 GNMUEVRJHCWKTO-FQEVSTJZSA-N 1S/C25H22ClN5O2S/c1-13-14(2)34-25-22(13)23(16-4-6-17(26)7-5-16)28-20(24-30-29-15(3)31(24)25)12-21(33)27-18-8-10-19(32)11-9-18/h4-11,20,32H,12H2,1-3H3,(H,27,33) SIGMA-ALDRICH powder ≥98% (HPLC)
£1,098.96 (exc VAT) per 25MG
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3575145 OTX015 white to light brown 100 GNMUEVRJHCWKTO-FQEVSTJZSA-N 1S/C25H22ClN5O2S/c1-13-14(2)34-25-22(13)23(16-4-6-17(26)7-5-16)28-20(24-30-29-15(3)31(24)25)12-21(33)27-18-8-10-19(32)11-9-18/h4-11,20,32H,12H2,1-3H3,(H,27,33) SIGMA-ALDRICH powder ≥98% (HPLC)
£355.18 (exc VAT) per 5MG
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