O-Acetyl-L-carnitine hydrochloride, >=99% (titration), powder

O-Acetyl-L-carnitine hydrochloride, >=99% (titration), powder

Application

O-Acetyl-L-carnitine hydrochloride has been used: as a bioactive compound to study its effect on the proliferation of B-lymphoblastoid cell lines (BLCL) and its immune modulating properties on influenza virus specific human B and T cell responses in vitroas in vitro maturation (IVM) media component to study its effects on lamb oocyte blastocyst rate, ultrastructure and mitochondrial DNA copy number as a metabolite/chemical standard to quantify the metabolite levels in murine tumor interstitial fluid

Biochem/physiol Actions

Endogenous mitochondrial metabolite that transports acetyl groups across the mitochondrial membrane. Exogenous acetylcarnitine enhances mitochondrial function in aged rats. As an acetate donor to coenzyme A, it increases the central and peripheral acetylcholine synthesis and function. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.

Acetyl L-carnitine (ALC) plays a vital role in intermediary metabolism and in improving female fertility. The oxidative and metabolic status of the female reproductive system is controlled by ALC. ALC possesses cholinomimetic and anti-inflammatory effects. It controls ?-amino butyric acid (GABA) system. ALC is capable of modifying the rate of glucose usage in the brain. It also possesses a neuroprotective role in the developing brain.

General description

Acetyl-L-carnitine (ALC/ALCAR), a quasi-vitamin is a metabolite of carnitine, present in mammalian plasma and tissues. It is the acetylated form of L-carnitine (LC). ALCAR is used as a dietary supplement. It is present at high level in the hypothalamus.

Packaging

1, 5 g in poly bottle

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Code Description Colour mp InChI key InChI Manufacturer Form Assay Price Quantity
3578091 O-Acetyl-L-carnitine hydrochloride, >=99% (titration), powder white to off-white 194 °C JATPLOXBFFRHDN-DDWIOCJRSA-N 1S/C9H17NO4.ClH/c1-7(11)14-8(5-9(12)13)6-10(2,3)4;/h8H,5-6H2,1-4H3;1H/t8-;/m1./s1 SIGMA-ALDRICH powder ≥99% (titration)
£46.14 (exc VAT) per 1G
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3578092 O-Acetyl-L-carnitine hydrochloride, >=99% (titration), powder white to off-white 194 °C JATPLOXBFFRHDN-DDWIOCJRSA-N 1S/C9H17NO4.ClH/c1-7(11)14-8(5-9(12)13)6-10(2,3)4;/h8H,5-6H2,1-4H3;1H/t8-;/m1./s1 SIGMA-ALDRICH powder ≥99% (titration)
£153.36 (exc VAT) per 5G
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