NSC130813

NSC130813

Biochem/physiol Actions

NSC130813 blocks protein-protein interactions between XPF and ERCC1, two proteins involved in nucleotide excision repair (NER). The compound, NSC130813, blocks repair of DNA damage induced by platinum-based ctyotoxic drugs and DNA alkylating agents. NSC130813 synergistically potentiates cell death in cancer cell lines treated with cisplatin or mitomycin C.

Other Notes

air sensitive

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3574250 NSC130813 yellow to orange 100 SIGMA-ALDRICH −20°C
£552.96 (exc VAT) per 25MG
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3574251 NSC130813 yellow to orange 100 SIGMA-ALDRICH −20°C
£182.46 (exc VAT) per 5MG
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