Nicotinamide, BioReagent, suitable for cell culture, suitable for insect cell culture

Nicotinamide, BioReagent, suitable for cell culture, suitable for insect cell culture

Application

Nicotinamide has been used as a medium supplement in organoid culture of intestinal stem cells, esophageal squamous cell carcinomas(ESCC), pancreatic cancer organoids and pancreatic progenitor induction.

Biochem/physiol Actions

Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

General description

Nicotinamide (NAM) belongs to vitamin B family and is the amide form of vitamin B3. NAM is present in food and is a constituent of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). Tryptophan is the precursor for NAM synthesis in liver. NAM controls cell metabolism, redox reactions, mitochondrial functionsand energy generation. It promotes natural killer cells proliferation and survival. NAM confers neuroprotection and promotes neuronal maturation. It has the ability to cross the blood-brain barrier and may provide protection in ischaemic stroke and traumatic brain injury. NAM may elicit therapeutic benefits in Alzheimer?s, Parkinson?s, and Huntington?s diseases.

Packaging

100, 500 g in poly bottle

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Code Description Colour Pack InChI key InChI Manufacturer Form Assay Price Quantity
3572100 Nicotinamide, BioReagent, suitable for cell culture, suitable for insect cell culture white 100G DFPAKSUCGFBDDF-UHFFFAOYSA-N 1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
£47.31 (exc VAT) per 100G
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3572101 Nicotinamide, BioReagent, suitable for cell culture, suitable for insect cell culture white 500G DFPAKSUCGFBDDF-UHFFFAOYSA-N 1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
£208.75 (exc VAT) per 500G
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