NELARABINE

NELARABINE

Biochem/physiol Actions

Nelarabine is an antineoplastic purine nucleoside analog used in T-cell acute lymphoblastic leukemia. It is a pro-drug of Ara-G, which is converted by cellular kinases to the active 5′-triphosphate, Ara-GTP. Incorporation of Ara-GTP into DNA leads to inhibition of DNA synthesis and apoptosis.

Packaging

10, 50 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3575324 NELARABINE white to beige 100 IXOXBSCIXZEQEQ-KBNQYOMWSA-N 1S/C11H15N5O5/c1-20-9-5-8(14-11(12)15-9)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15)/t4-,6-,7+,10?/m1/s1 SIGMA-ALDRICH H2O: 5 mg/mL, clear (warmed) powder ≥98% (HPLC)
£131.76 (exc VAT) per 10MG
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3575325 NELARABINE white to beige 100 IXOXBSCIXZEQEQ-KBNQYOMWSA-N 1S/C11H15N5O5/c1-20-9-5-8(14-11(12)15-9)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15)/t4-,6-,7+,10?/m1/s1 SIGMA-ALDRICH H2O: 5 mg/mL, clear (warmed) powder ≥98% (HPLC)
£536.25 (exc VAT) per 50MG
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