NED-K

NED-K

Biochem/physiol Actions

Ned-K is a specific and potent inhibitor of NAADP (nicotinic acid adenine dinucleotide phosphate) signaling that suppresses Ca2+ oscillations via two-pore channels (TPC1) and opening of the mitochondrial permeability transition pore (mPTP) in cardiomyocytes during simulated ischaemia and reperfusion. Ned-K protected cardiomyocytes from cell death during ischaemia and reperfusion injury in rats.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575844 NED-K white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£537.64 (exc VAT) per 25MG
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3575845 NED-K white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£169.93 (exc VAT) per 5MG
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