N-Methyl-D-aspartic acid, >=98% (TLC), solid

N-Methyl-D-aspartic acid, >=98% (TLC), solid

Application

N-Methyl-D-aspartic acid has been used to induce N-methyl-d-aspartic acid (NMDA) toxicity, cultures of retinal cells were supplemented with NMDA.

Biochem/physiol Actions

Excitotoxic amino acid. Prototypic agonist at the NMDA-type glutamate receptor that regulates ion channels; important in long-term potentiation, ischemia, and epilepsy.

N-Methyl-D-aspartic acid (NMDA) plays a crucial role in release of luteinizing hormone and PRL (prolactin) in the pituitary gland and GnRH (gonadotropin releasing hormone) in the hypothalamus. It acts as a specific agonist for NMDA type glutamate receptors.

General description

N-Methyl-D-aspartic acid (NMDA) is an endogenously generated molecule in rat nervous system and endocrine glands. NMDA is present at low level (nmol/g) in the adenohypophysis, hypothalamus, brain, and testis. NMDA is derived from D-Asp by an S-adenosylmethionine-dependent enzyme also referred to as NMDA synthase.

Packaging

1, 5 g in poly bottle

25, 100, 250 mg in poly bottle

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Code Description Colour mp InChI key InChI Manufacturer Form Assay Price Quantity
3591757 N-Methyl-D-aspartic acid, >=98% (TLC), solid white 189-190 °C HOKKHZGPKSLGJE-GSVOUGTGSA-N 1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m1/s1 SIGMA-ALDRICH solid ≥98% (TLC)
£169.64 (exc VAT) per 100MG
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3591758 N-Methyl-D-aspartic acid, >=98% (TLC), solid white 189-190 °C HOKKHZGPKSLGJE-GSVOUGTGSA-N 1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m1/s1 SIGMA-ALDRICH solid ≥98% (TLC)
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3591759 N-Methyl-D-aspartic acid, >=98% (TLC), solid white 189-190 °C HOKKHZGPKSLGJE-GSVOUGTGSA-N 1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m1/s1 SIGMA-ALDRICH solid ≥98% (TLC)
£409.86 (exc VAT) per 250MG
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3591760 N-Methyl-D-aspartic acid, >=98% (TLC), solid white 189-190 °C HOKKHZGPKSLGJE-GSVOUGTGSA-N 1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m1/s1 SIGMA-ALDRICH solid ≥98% (TLC)
£68.26 (exc VAT) per 25MG
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