MONNA

MONNA

Biochem/physiol Actions

MONNA is a TMEM16A (ANO1) calcium-activated chloride channel blocker. MONNA blocks rhTMEM16A (ANO1) channel currents in HEK293 cells with and IC50 of 1.27 µM. The compound MONNA does not affect related human or mouse chloride channels bestrophin-1, CLC2 and CFTR at concentrations up to 10 µM.

MONNA (benzbromarone (Benzb) and N-((4-methoxy)-2-naphthyl)-5-nitroanthranilic acid) is a TMEM16A antagonists. It affects the liberation of sarcoplasmic reticulum (SR) calcium in human airway smooth muscle cells.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3574221 MONNA light orange to dark orange 100 SIGMA-ALDRICH 2-8°C
£594.75 (exc VAT) per 25MG
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3574222 MONNA light orange to dark orange 100 SIGMA-ALDRICH 2-8°C
£153.21 (exc VAT) per 5MG
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