ML327

Biochem/physiol Actions

ML327 is a regulator of E-cadherin transcription that restores E-cadherin expression in cancer cell lines and partially reverses Epithelial-to-Mesenchymal Transition (EMT). It is a potent inducer of mesenchymal-to-epithelial transition (MET) in epithelial cancers. Apparently ML327 blocks MYC expression in neuroblastomas. It induces apoptosis in cancer cells and sensitizes Ewing sarcoma cells to TRAIL.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576263 ML327 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£600.32 (exc VAT) per 25MG
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3576264 ML327 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£185.25 (exc VAT) per 5MG
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