Lomerizine dihydrochloride, >=98% (HPLC), powder

Lomerizine dihydrochloride, >=98% (HPLC), powder

Biochem/physiol Actions

Lomerizine dihydrochloride is a voltage-dependent calcium channel blocker and selective cerebral vasodilator. It is one of the most selective calcium channel blockers for the CNS and cerebral arteries. It has been reported to inhibit both T-type and L-type Ca2+ currents in rat hippocampal CA1 pyramidal neurons, to prevent glutamate-induced neurotoxicity in rat hippocampal primary cell cultures, and to exhibit protective effects in animal models of migraine, ischemia and hypoxia. In Japan, lomerizine has been used as the first-line prophylactic drug for migraines.

Packaging

10, 50 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3573441 Lomerizine dihydrochloride, >=98% (HPLC), powder white to tan 100 LOGVKVSFYBBUAJ-UHFFFAOYSA-N 1S/C27H30F2N2O3.2ClH/c1-32-24-13-8-21(26(33-2)27(24)34-3)18-30-14-16-31(17-15-30)25(19-4-9-22(28)10-5-19)20-6-11-23(29)12-7-20;;/h4-13,25H,14-18H2,1-3H3;2*1H
£143.46 (exc VAT) per 10MG
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3573442 Lomerizine dihydrochloride, >=98% (HPLC), powder white to tan 100 LOGVKVSFYBBUAJ-UHFFFAOYSA-N 1S/C27H30F2N2O3.2ClH/c1-32-24-13-8-21(26(33-2)27(24)34-3)18-30-14-16-31(17-15-30)25(19-4-9-22(28)10-5-19)20-6-11-23(29)12-7-20;;/h4-13,25H,14-18H2,1-3H3;2*1H
£480.54 (exc VAT) per 50MG
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