Levocetirizine dihydrochloride, >=98% (HPLC)

Levocetirizine dihydrochloride, >=98% (HPLC)

Application

Levocetirizine dihydrochloride has been used as standard in the thin layer chromatography optimization and in preparation of racemic cetirizine standard for subcritical fluid chromatography-tandem mass spectrometry analysis.

Biochem/physiol Actions

Levocetirizine hydrochloride is a nonsedating antihistamine. It is a histamine H1-receptor antagonist, the active isomer of cetirizine. Levocetirizine has high bioavailability, high affinity for and occupancy of the H1 receptor.

Features and Benefits

This compound was developed by Pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

General description

Levocetirizine dihydrochloride is the R-enantiomer of cetirizine and is used for treating seasonal allergic rhinitis and chronic idiopathic urticaria. The liver metabolizes 14% of levocetirizine and rest is excreted in urine. The response of levocetirizine to histamine is comparatively higher to cetirizine.

Packaging

10, 50 mg in glass bottle

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Code Description Quality Level InChI key InChI Manufacturer Form Assay Price Quantity
3573449 Levocetirizine dihydrochloride, >=98% (HPLC) 100 PGLIUCLTXOYQMV-GHVWMZMZSA-N 1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H/t21-;;/m1../s1 SIGMA-ALDRICH
£146.25 (exc VAT) per 10MG
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3573450 Levocetirizine dihydrochloride, >=98% (HPLC) 100 PGLIUCLTXOYQMV-GHVWMZMZSA-N 1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H/t21-;;/m1../s1 SIGMA-ALDRICH
£434.57 (exc VAT) per 50MG
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