Lectin from Arachis hypogaea (peanut), lyophilized powder, Affinity-purified

Analysis Note

Agglutination activity is expressed in µg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, of a 1 mg/ml solution. This activity is the lowest concentration to agglutinate a 2% suspension of neuraminidase treated human blood group O erythrocytes after 1 hr incubation at 25 °C.

Application

Lectin from Arachis hypogaea (peanut) has been used:to detect Thomson-Friedenreich antigenas a component in PBS to study its effects on cell viabilityto study its ability to block the binding site

Biochem/physiol Actions

PNA does not agglutinate normal human erythrocytes, but strongly agglutinates neuraminidase treated erythrocytes. PNA has potent anti-T activity similar to the anti-T antibody in human sera. The lectin can be used to distinguish between human lymphocyte subsets.

Lectin from Arachis hypogaea (peanut) possess specificity towards ? -D-Gal(1-3)-D-galNAc residue of Thomson ? Friedenreich antigen. It is the most widely used diagnostic and prognostic marker for many squamous cell carcinomas.

General description

Lectin from Arachis hypogaea (peanut) is a homotetrameric protein of 110 kDa.

Packaging

5, 10, 25 mg in glass bottle

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Code Description Quality Level Manufacturer Storage Temp. Impurities Form Price Quantity
3587028 Lectin from Arachis hypogaea (peanut), lyophilized powder, Affinity-purified 200 SIGMA-ALDRICH −20°C salt, free
£270.21 (exc VAT) per 10MG
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3587029 Lectin from Arachis hypogaea (peanut), lyophilized powder, Affinity-purified 200 SIGMA-ALDRICH −20°C salt, free
£530.68 (exc VAT) per 25MG
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3587030 Lectin from Arachis hypogaea (peanut), lyophilized powder, Affinity-purified 200 SIGMA-ALDRICH −20°C salt, free
£153.21 (exc VAT) per 5MG
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