LAPATINIB

LAPATINIB

Biochem/physiol Actions

Lapatinib acts as a dual tyrosine kinase inhibitor of epidermal growth factor receptor (EGFR/ErbB1) and human epidermal growth factor receptor 2(HER2/ErbB2). It competes for its binding site on the tyrosine kinase domain with adenosine triphosphate (ATP). Lapatinib mediates has been studied in vitro in the inhibition of cell growth as well as and apoptosis induction in several human cancer cells such as breast, lung, vulva, gastric, and head and neck cancer.

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Code Description Colour InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3576045 LAPATINIB white to beige BCFGMOOMADDAQU-UHFFFAOYSA-N 1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18 SIGMA-ALDRICH
£77.16 (exc VAT) per 10MG
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3576046 LAPATINIB white to beige BCFGMOOMADDAQU-UHFFFAOYSA-N 1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18 SIGMA-ALDRICH
£312.00 (exc VAT) per 50MG
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