L-Buthionine-sulfoximine, >=97% (TLC)

L-Buthionine-sulfoximine, >=97% (TLC)

Application

Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.

L-Buthionine-sulfoximine has been used:as a selective activator for the induction of ferroptosis in rat apoptotic cellsas an inhibitor of ?-glutamylcysteine synthetase to study its effects on the viability and effectiveness of microspore embryogenesis (ME) induction in triticale and barleyas a glutathione synthesis blocker to study its effects on auranofin (AFN)-mediated interleukin-1? expression in murine alveolar macrophages

Biochem/physiol Actions

Blocks cellular resistance to chemotherapy by inhibiting γ-glutamylcysteine synthetase, a key enzyme in glutathione biosynthesis. Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.

Packaging

1, 5 g in poly bottle

500 mg in poly bottle

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Code Description Quality Level mp InChI key InChI Manufacturer Form Assay Price Quantity
3577640 L-Buthionine-sulfoximine, >=97% (TLC) 200 224-226 °C KJQFBVYMGADDTQ-CVSPRKDYSA-N 1S/C8H18N2O3S/c1-2-3-5-14(10,13)6-4-7(9)8(11)12/h7,10H,2-6,9H2,1H3,(H,11,12)/t7-,14?/m0/s1
£442.93 (exc VAT) per 1G
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3577641 L-Buthionine-sulfoximine, >=97% (TLC) 200 224-226 °C KJQFBVYMGADDTQ-CVSPRKDYSA-N 1S/C8H18N2O3S/c1-2-3-5-14(10,13)6-4-7(9)8(11)12/h7,10H,2-6,9H2,1H3,(H,11,12)/t7-,14?/m0/s1
£240.96 (exc VAT) per 500MG
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3577642 L-Buthionine-sulfoximine, >=97% (TLC) 200 224-226 °C KJQFBVYMGADDTQ-CVSPRKDYSA-N 1S/C8H18N2O3S/c1-2-3-5-14(10,13)6-4-7(9)8(11)12/h7,10H,2-6,9H2,1H3,(H,11,12)/t7-,14?/m0/s1
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