L-742001

Biochem/physiol Actions

L-742,001 is an inhibitor of the influenza virus RNA polymerase PA subunit, implicated in several roles, including endonuclease and protease activities as well as viral RNA/complementary RNA promoter binding. L-742,001 inhibits the influenza endonuclease-dependent polymerase activity with an IC50 of 430 nM.

L-742001 is useful in the treatment of influenza viral infection.

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Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3574353 L-742001 white to beige 100 LMLNSXCRZNNZBT-VSOKSMTPSA-N 1S/C23H24ClNO4.ClH/c24-19-8-6-17(7-9-19)15-23(21(27)14-20(26)22(28)29)10-12-25(13-11-23)16-18-4-2-1-3-5-18;/h1-9,14,26H,10-13,15-16H2,(H,28,29);1H/b20-14-; SIGMA-ALDRICH DMSO: 20 mg/mL, clear powder ≥98% (HPLC)
£516.75 (exc VAT) per 25MG
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3574354 L-742001 white to beige 100 LMLNSXCRZNNZBT-VSOKSMTPSA-N 1S/C23H24ClNO4.ClH/c24-19-8-6-17(7-9-19)15-23(21(27)14-20(26)22(28)29)10-12-25(13-11-23)16-18-4-2-1-3-5-18;/h1-9,14,26H,10-13,15-16H2,(H,28,29);1H/b20-14-; SIGMA-ALDRICH DMSO: 20 mg/mL, clear powder ≥98% (HPLC)
£172.71 (exc VAT) per 5MG
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