KEA1-97

KEA1-97

Biochem/physiol Actions

KEA1-97 is a Thioredoxin-Caspase 3 interaction disruptor. It was found to target lysine 72 of thioredoxin, inhibiting its interactions with caspase 3 and inducing apoptosis without affecting other thioredoxin activity. KEA1-97 induced apoptosis in breast cancer cells and treatment of immune-deficient SCID mice at 5 mg/kg ip impaired breast tumor xenograft growth.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575922 KEA1-97 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£402.54 (exc VAT) per 25MG
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3575923 KEA1-97 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£99.45 (exc VAT) per 5MG
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