KCC-07

Biochem/physiol Actions

KCC-07 is a brain penetrant, potent and selective inhibitor of MBD2 (methyl-CpG-binding domain protein 2) that inhibits binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling. KCC-07 inhibits medulloblastoma cell proliferation, and inhibits tumor growth in mice xenograft models of medulloblastoma.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576471 KCC-07 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£501.43 (exc VAT) per 25MG
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3576472 KCC-07 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£124.24 (exc VAT) per 5MG
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