JI130

JI130

Biochem/physiol Actions

JI130 is a cell penetrant, potent and selective inhibitor of the helix-loop-helix transcription factor Hes1 that blocks Hes1-mediated transcriptional repression. JI130 potently inhibits pancreatic cancer cell lines proliferation, and shrink tumor in a mice pancreatic tumor xenograft model.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576271 JI130 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear powder ≥95% (HPLC)
£388.61 (exc VAT) per 25MG
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3576272 JI130 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear powder ≥95% (HPLC)
£89.14 (exc VAT) per 5MG
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