JH-II-127

JH-II-127

Biochem/physiol Actions

JH-II-127 is an orally available, brain penetrant, potent and selective inhibitor of both wild-type and G2019S mutant Leucine-rich repeat kinase 2 (LRRK2). JH-II-127 inhibits phosphorylation of the Ser910 and Ser935 of both wild-type and G2019S mutant LRRK2. It causes complete inhibition of LRRK2 in mouse brain at 100 mg/kg.

No detailed specifications are available for this product.

There are no downloads for this product.

Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576510 JH-II-127 white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£486.11 (exc VAT) per 25MG
-
+
3576511 JH-II-127 white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£151.82 (exc VAT) per 5MG
-
+