JH-I-25

Biochem/physiol Actions

JH-I-25 is a potent and selective type I inhibitor of IRAK1 and IRAK4 (interleukin-1 receptor–associated kinase 1 and 4). JH-I-25 binds preferentially to the unphosphorylated the ATP-site of the kinase in its active, DFG-in, state.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576577 JH-I-25 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear (warmed)
£533.46 (exc VAT) per EACH
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3576578 JH-I-25 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear (warmed)
£165.75 (exc VAT) per EACH
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