Iodoacetic acid, >=98.0% (T)

Iodoacetic acid, >=98.0% (T)

Application

Reagent for the modification of cysteine residues in proteins.

Iodoacetic acid has been used as an alkylating agent for antibody AR37, serum proteins and strawberry proteome samples extracted from different stages of ripened fruit.

Biochem/physiol Actions

Iodoacetic acid (IAA) blocks the thiol group of cysteine. IAA inhibits glyceraldehyde-3-phosphate dehydrogenase (G3PDH) by interacting with sulfhydryl group of the active site cysteine. IAA inhibits the progression of solid Ehrlich carcinoma. IAA is one of the iodinated disinfection byproducts in drinking water. It is cytotoxic to mammalian cells.

Packaging

10, 25, 100 g in glass bottle

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Code Description Colour Quality Level mp InChI key InChI Manufacturer Form Assay Price Quantity
3577809 Iodoacetic acid, >=98.0% (T) white to yellow 200 77-79 °C (lit.) JDNTWHVOXJZDSN-UHFFFAOYSA-N 1S/C2H3IO2/c3-1-2(4)5/h1H2,(H,4,5) SIGMA-ALDRICH powder or flakes ≥98.0% (T)
£222.00 (exc VAT) per 100G
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3577810 Iodoacetic acid, >=98.0% (T) white to yellow 200 77-79 °C (lit.) JDNTWHVOXJZDSN-UHFFFAOYSA-N 1S/C2H3IO2/c3-1-2(4)5/h1H2,(H,4,5) SIGMA-ALDRICH powder or flakes ≥98.0% (T)
£38.85 (exc VAT) per 10G
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3577811 Iodoacetic acid, >=98.0% (T) white to yellow 200 77-79 °C (lit.) JDNTWHVOXJZDSN-UHFFFAOYSA-N 1S/C2H3IO2/c3-1-2(4)5/h1H2,(H,4,5) SIGMA-ALDRICH powder or flakes ≥98.0% (T)
£79.81 (exc VAT) per 25G
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