Insulin human has been used:in the culture medium needed for the adipogenesis of ASCs (adipose-derived stem cells)to study the effect of insulin in the young and aged brains of rats.to study the effect of insulin on the inflammatory actions of protease-activated receptor 2 (PAR2) using mice model.
Biochem/physiol Actions
Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.