IMM-01

IMM-01

Application

IMM-01 has been used as a formin activator to study its effects on motor neurons (MNs).

Biochem/physiol Actions

IMM-01 binds and activates formin thereby leading to autoinhinition.

IMM-01 is an agonist of the mammalian Diaphanous (mDia)-related formins that triggers actin assembly and microtubule stabilization, serum response factor-mediated gene expression, cell-cycle arrest, and apoptosis. IMM-01 inhibits DID–DAD binding, which in turn activates mDia family of formins in cells. IMM-01 slows tumor growth in a mouse xenograft model of colon cancer.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3574417 IMM-01 white to light brown 100 SIGMA-ALDRICH 2-8°C
£594.75 (exc VAT) per 25MG
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3574418 IMM-01 white to light brown 100 SIGMA-ALDRICH 2-8°C
£150.43 (exc VAT) per 5MG
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